Research

The project is multidisciplinary and operated at the Department of Veterinary Pathology, Veterinary Public Health & Epidemiology and Department of Veterinary Parasitology under the efficient and learned faculties.

Based on the sampling frame designed by the ICAR-NIVEDI, Bangalore the samples from the various animal hosts are collected for their screening by the serological and molecular techniques. The SOPs contributed by various centres are strictly followed for uniformity among the data generated. The medical counterpart included in the network also contributes for the parallel screening and human counterpart.

Objectives of the project are:

1. To establish a network of laboratories at centralized and field levels
2. To estimate prevalence and burden of selected diseases through serological or other surveillance methods.
3. To detect pathogens by serological (antigen) or molecular tests where disease symptoms clearly manifest, mainly in clinical cases and when required in animals.
4. To model the data for disease forecasting and assess risk
5. To generate tools and reagents.

The major transboundry diseases under study with “One Health Centre” at Nagpur Veterinary College, Nagpur are: 

• Tuberculosis
• Brucellosis
• JE
• Cryptosporidiosis
• Cysticercosis
• Q fever
• Salmonellosis
• Listeriosis
• LSD

 The study area for the centre under the project is Maharashtra, Goa, Chhattisgarh and Madhya Pradesh  

Deliverables

The deliverables of the network project will be:

1. The availability of state-wise and nation-wide data on the selected zoonotic diseases and TADs,
2. The validation of indigenous tests for use in the field, in cases where no commercial OIE/WHO/CDC recommended kits are available, but other commercial kits or proof-of-concept assays are available,
3. Valuable reference (positive and negative) sera banks for each disease at multiple places,
4. The development of platforms such as monoclonal antibody facility and generation of laboratory animal models (only 5% effort of the project),
5. The establishment of a network of veterinary and medical centres and laboratories to work together so as to lay the foundation for continuous monitoring of diseases as well as for future One Health – related work,
6. Investment towards border security in terms of incursion of pathogens, and
7. A roadmap to provide strategy for a continuing endeavour and a sustainability pathway for One Health programme in India.